Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Waves01:23

Brain Waves

4.1K
Brain waves are electrical signals generated by the neurons in the brain, which are regularly monitored to measure mental activities. Brain waves and their frequency ranges can be measured using an electroencephalogram or EEG. There are four main types of brain waves, each with distinct characteristics:
4.1K
Organization of the Brain01:30

Organization of the Brain

2.6K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
2.6K
Brain Imaging01:14

Brain Imaging

724
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
724
Anatomy of the Brain: Ventricles01:18

Anatomy of the Brain: Ventricles

8.6K
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
8.6K
The Blood-brain Barrier00:49

The Blood-brain Barrier

52.7K
Overview
52.7K
Neurons as Communicators of the Brain01:22

Neurons as Communicators of the Brain

3.1K
Neurons, the fundamental units of the brain and nervous system, function as the primary transmitters of information throughout the body. Their ability to communicate through electrical and chemical signals is vital for every bodily function, from regulating the heartbeat to processing complex thoughts. Each neuron has three main components: the cell body (soma), dendrites, and an axon, each specialized to facilitate swift and efficient neural communication.
Cell Body
The cell body, also known...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in serotonin neurotransmission as assayed by microdialysis after acute, intermittent or chronic ethanol administration and withdrawal.

Fundamental & clinical pharmacology·2023
Same author

Iron, Neuroinflammation and Neurodegeneration.

International journal of molecular sciences·2022
Same author

Changes in Brain Dopamine Extracellular Concentration after Ethanol Administration; Rat Microdialysis Studies.

Alcohol and alcoholism (Oxford, Oxfordshire)·2021
Same author

Is Chelation Therapy a Potential Treatment for Parkinson's Disease?

International journal of molecular sciences·2021
Same author

Iron and inflammation: in vivo and post-mortem studies in Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996)·2020
Same author

The Efficacy of Iron Chelators for Removing Iron from Specific Brain Regions and the Pituitary-Ironing out the Brain.

Pharmaceuticals (Basel, Switzerland)·2019
Same journal

Zinc Fingers.

Metal ions in life sciences·2020
Same journal

Nickel, Iron, Sulfur Sites.

Metal ions in life sciences·2020
Same journal

The Siroheme-[4Fe-4S] Coupled Center.

Metal ions in life sciences·2020
Same journal

Molybdenum and Tungsten Cofactors and the Reactions They Catalyze.

Metal ions in life sciences·2020
Same journal

The Cofactors of Nitrogenases.

Metal ions in life sciences·2020
Same journal

Basic Iron-Sulfur Centers.

Metal ions in life sciences·2020
See all related articles

Related Experiment Video

Updated: Jan 28, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.4K

Ironing out the Brain.

Roberta J Ward, Robert R Crichton

    Metal Ions in Life Sciences
    |March 12, 2019
    PubMed
    Summary
    This summary is machine-generated.

    Brain iron homeostasis is not well understood, impacting neurodegenerative diseases. Research explores iron transport, regulation, and its role in conditions like Parkinson's and Alzheimer's, with potential therapeutic targets in iron chelation.

    More Related Videos

    Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
    07:32

    Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

    Published on: May 23, 2025

    1.2K
    Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
    05:08

    Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

    Published on: January 31, 2022

    5.6K

    Related Experiment Videos

    Last Updated: Jan 28, 2026

    Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
    08:45

    Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

    Published on: May 10, 2022

    2.4K
    Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
    07:32

    Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining

    Published on: May 23, 2025

    1.2K
    Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
    05:08

    Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

    Published on: January 31, 2022

    5.6K

    Area of Science:

    • Neuroscience
    • Biochemistry
    • Cellular Biology

    Background:

    • Mammalian iron metabolism is established, but brain iron homeostasis remains poorly understood.
    • The distribution and function of iron metabolism proteins in the brain are uncertain.
    • Mechanisms of iron transfer across the blood-brain barrier are not fully elucidated.

    Purpose of the Study:

    • To review current concepts of iron uptake, distribution, and regulation in the brain.
    • To discuss the age-related increase in brain iron and its various forms.
    • To explore the link between aberrant brain iron levels and neurodegenerative diseases.

    Main Methods:

    • Review of existing literature on brain iron metabolism and homeostasis.
    • Discussion of iron distribution across different brain regions.
    • Analysis of the role of iron in neuroinflammation and neurodegeneration.

    Main Results:

    • Iron distribution in the brain varies by region and increases with normal aging.
    • Specific brain regions show elevated iron levels, implicated in neurodegenerative diseases.
    • Interactions between neuroinflammation and iron dysregulation are significant.

    Conclusions:

    • Understanding brain iron homeostasis is critical for neurodegenerative disease research.
    • Aberrant iron accumulation is a potential factor in diseases like Parkinson's and Alzheimer's.
    • Iron chelation therapy shows potential for treating neurodegenerative conditions.