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Related Experiment Video

Updated: Jan 28, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

Perioperative systemic therapy for bladder cancer.

Patrick J Eulitt¹, Marc A Bjurlin^2,3, Matthew I Milowsky^1,3

¹Division of Hematology/Oncology, Department of Medicine.

Current Opinion in Urology

|March 12, 2019

Summary

Advances in biomarkers and immunotherapy show promise for transforming perioperative systemic therapy in bladder cancer patients. These innovations may soon improve treatment selection and outcomes for muscle-invasive bladder cancer.

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Last Updated: Jan 28, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools

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Published on: December 28, 2021

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

Area of Science:

Oncology
Urology
Cancer Research

Background:

Bladder cancer treatment is evolving with new therapeutic strategies.
Perioperative systemic therapy plays a crucial role in managing bladder cancer.

Purpose of the Study:

To review recent advances in biomarkers and immunotherapy for bladder cancer.
To explore the potential impact on perioperative systemic therapy.
To discuss the implications for muscle-invasive bladder cancer.

Main Methods:

Review of current research on predictive biomarkers.
Analysis of immunotherapy trials in bladder cancer.
Evaluation of neoadjuvant chemotherapy selection strategies.

Main Results:

Predictive biomarkers like DNA damage repair genes and gene expression profiling are emerging for patient selection.
Immunotherapy, successful in metastatic disease, is being explored in muscle-invasive bladder cancer.
Ongoing trials incorporating biomarkers and immunotherapy show potential for improved outcomes.

Conclusions:

Biomarker research and immunotherapy advancements hold significant potential for bladder cancer treatment.
These innovations may personalize perioperative systemic therapy for better patient outcomes.
Further research and clinical trials are crucial to realize the full impact on muscle-invasive bladder cancer.