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Updated: Jan 28, 2026
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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
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All-cause hospitalizations in multiple sclerosis patients.
Revista De Neurologia
|March 12, 2019
Summary
Infections are the leading cause of hospitalizations in multiple sclerosis (MS) patients, though MS relapses also contribute significantly. Intensive care unit admissions in MS patients are linked to longer hospital stays and increased mortality.
Area of Science:
- Neurology
- Clinical Medicine
- Epidemiology
Background:
- Limited understanding of current hospitalization patterns in the multiple sclerosis (MS) population.
- Need for data on causes and outcomes of MS patient hospitalizations.
Purpose of the Study:
- To investigate the primary reasons for hospitalization among patients with multiple sclerosis.
- To analyze the outcomes of hospitalizations within a hospital-based MS cohort.
Main Methods:
- Retrospective chart review of MS patients admitted between August 2009 and July 2015.
- Inclusion criteria: patients with a pre-existing diagnosis of multiple sclerosis.
Main Results:
- 308 hospitalizations from 155 MS patients were analyzed.
- Infectious diseases (22.1%) were the most frequent cause, followed by MS relapses (12.7%) and neurogenic bladder (11%).
- Intensive care unit admission (7.5%) correlated with higher mortality and longer hospital stays.
Conclusions:
- Infections are the primary driver of hospitalizations in this MS cohort.
- MS relapses and complications remain significant causes of morbidity.
- A notable percentage of MS hospitalizations require ICU care, associated with adverse outcomes.
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