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Sesquiterpenes from the fruits of Illicium Simonsii maxim
Hang Liu1, Minghua Chen2, Yongjun Lang3
1Department of Pharmacy, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, China.
Abstract:
A new allo-cedrane sesquiterpene glycoside (1) and nine known compounds (2-10) were isolated from the ethanol extract of the fruit of Illicium simonii Maxim. Their structures were elucidated by spectroscopic methods, including 1D-, 2D-NMR, and HRESIMS. The absolute configuration of compound 1 was confirmed by CD experiments. Among them, compounds 1, 4, 5, and 7 displayed moderate anti-inflammatory activities by use of an in vitro bioassay.
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