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The effect of hypoxia on the activity of purine nucleoside phosphorylase in rats
Abstract:
The activity of purine nucleoside phosphorylase (PNP) in rat erythrocytes fractionated by centrifugation in microhematocrit capillaries was studied. After seven-day hypoxia (54 kPa) the PNP activity was increased by 67 +/- 4% (S.E.M.) in the lightest fraction of erythrocytes; on the fifth day after hypoxia PNP activity did not differ from control values.