Related Experiment Video
Updated: Jan 28, 2026

Assessment of Waste-Derived Biochars on the Health and Biological Activity of Soil
Published on: October 10, 2025
Two new phenazine metabolites with antimicrobial activities from soil-derived Streptomyces species
Linfang Hu1, Xiao Chen1, Li Han2
1Key Laboratory of Microbial Diversity in Southwest China, Ministry of Education, College of Life Science, Yunnan University, 650091, Kunming, China.
Abstract:
Two new phenazine metabolites, 6-hydroxyphenazine-1-carboxamide (1) and methyl 6-carbamoylphenazine-1-carboxylate (2), were isolated from a soil-derived Streptomyces diastaticus subsp. ardesiacus strain YIM PH20246, and their structures were elucidated by extensive spectroscopic data analysis. The antimicrobial activities of the isolates were assayed. Compound 1 showed moderate antifungal and antibacterial activities against Fusarium oxysporum (ATCC 7808), Fusarium solani (ATCC 36031) and Plectosphaerella cucumerina (local isolate), Staphylococcus aureus (ATCC 25923) and Staphylococcus albus (ATCC 10231), respectively. Compound 2 exhibited moderate antifungal and antibacterial activities against F. oxysporum, F. solani, and Phoma herbarum, S. aureus, S. albus, and Bacillus subtilis, respectively.
Related Concept Videos
The Soil Ecosystem
What is a Species?
Keystone Species
Formation of Species
Antimicrobial Effectiveness
Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug

