Related Experiment Video
Updated: Jan 28, 2026

19:16
The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
Published on: March 17, 2010
21.1K
Publisher Correction: Side chain determinants of biopolymer function during selection and replication
Phillip A Lichtor1,2, Zhen Chen1,2, Nadine H Elowe2
1Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Nature Chemical Biology
|March 13, 2019
Summary
This article corrects a production error in Figure 4c, ensuring accurate data presentation for scientific reproducibility. The updated figure is now correctly displayed in all versions.
Area of Science:
- Scientific communication
- Data integrity
Background:
- Accurate representation of scientific data is crucial for research integrity.
- Production errors can inadvertently alter data visualization.
Purpose of the Study:
- To correct a specific data misplacement in Figure 4c.
- To ensure the accurate depiction of experimental results.
Main Methods:
- Review of original article production files.
- Identification of data point misplacement in Figure 4c.
- Correction and re-insertion of the accurate figure.
Main Results:
- A production error in Figure 4c was identified.
- The data points in Figure 4c have been repositioned correctly.
- The corrected figure is now available in the article.
Conclusions:
- The correction ensures the integrity of the presented data.
- This ensures reliable interpretation of the study's findings.
- Accurate figures are essential for scientific literature.
Related Concept Videos
Chromosome Replication
10.6K
Before a cell can divide, it must accurately replicate all of its chromosomes, including the DNA and its associated histone and non-histone proteins. This process begins at numerous origins of replication during the S phase of the cell cycle in each of a cell’s chromosomes simultaneously. Certain nucleotides can act as origins of replication, but these sequences are not well defined - especially in complex, multi-cellular, eukaryotic species. The length of DNA that spans an origin...
10.6K
Distance Corrections
282
To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
282
DNA Replication
59.0K
DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied. After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
Replication in Prokaryotes
DNA replication...
59.0K
Replication in Prokaryotes
97.7K
Overview
97.7K
Replication in Prokaryotes
27.8K
DNA replication has three main steps: initiation, elongation, and termination. Replication in prokaryotes begins when initiator proteins bind to the single origin of replication (ori) on the cell's circular chromosome. Replication then proceeds around the entire circle of the chromosome in each direction from the two replication forks, resulting in two DNA molecules.
Many Proteins Work Together to Replicate the Chromosome
Replication is coordinated and carried out by a host of specialized...
Many Proteins Work Together to Replicate the Chromosome
Replication is coordinated and carried out by a host of specialized...
27.8K
Replication in Eukaryotes
204.4K
Overview
204.4K

