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Updated: Jan 28, 2026

An Alternative Approach for Sample Preparation with Low Cell Number for TEM Analysis
Published on: October 12, 2016
TAMIS is a valuable alternative to TEM for resection of intraluminal rectal tumors
F Van den Eynde1, J Jaekers1, S Fieuws2
1Department of Abdominal Surgery, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Background:
The aim of this study was to compare the short-term outcome after Transanal Endoscopic Microsurgery (TEM) and Transanal Minimally Invasive Surgery (TAMIS) for intraluminal rectal lesions.
Methods:
Retrospective analysis of a prospectively maintained database of all TEM and TAMIS procedures performed at a single institution by one surgeon between March 2009 and September 2017 was conducted. Primary outcome was operating time. Secondary outcomes were blood loss, pathological outcome, length of hospital stay, 30-day readmission and mortality.
Results:
Fifty-three patients underwent TEM procedure and 68 patients underwent TAMIS. Operating time was significantly shorter for TAMIS compared with TEM (median 45 vs 65 min, p < 0.0001). Blood loss was negligible for both TEM and TAMIS. Resection margins, lesion grade and invasion depth were comparable for both approaches. A significantly higher postoperative readmission rate was observed in the TEM group (17% vs 4.4%, p = 0.031). Mortality was zero in both groups.
Conclusions:
TAMIS is a valuable alternative to TEM, leading to decreased operating times, because all resections can be done in lithotomy position.
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