Variability of revascularization techniques among Catalan hospitals and impact on leg salvage in patients with peripheral arterial disease
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Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease
Published on: August 26, 2017
Ignasi Bolíbar1, Ignasi Gich2,3, Albert Anglès4
1Department of Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB de Sant Pau), Biomedical Research Center Network for Epidemiology and Public Health (CIBERESP), Autonomous University of Barcelona, Barcelona, Spain - ibolibar@santpau.cat.
Insights
Peripheral arterial disease (PAD) revascularization varies by hospital. Both endovascular and open surgery showed similar major amputation rates, but endovascular treatment had lower in-hospital mortality.
Area of Science:
- Vascular Surgery
- Health Services Research
- Public Health
Background:
- Peripheral arterial disease (PAD) treatment indications and practices vary significantly across healthcare facilities.
- This study examined revascularization techniques and amputation rates in PAD patients within the Catalan Health Service.
Purpose of the Study:
- To analyze patterns of revascularization techniques and amputation procedures for peripheral arterial disease (PAD).
- To investigate hospital variability in PAD treatment and compare outcomes of endovascular versus open surgical revascularization.
Main Methods:
- Utilized a clinical-administrative registry of hospital admissions in Catalonia, Spain (2009-2014).
- Analyzed patient clinical courses, hospital-specific revascularization techniques, and amputation rates.
- Compared outcomes, including patency, amputation rates, and mortality, between endovascular and open surgical approaches.
Main Results:
- PAD admissions totaled 9,828 annually, with 631 major amputations.
- Endovascular techniques were concentrated in high-tech hospitals, showing significant inter-hospital variability (ratio 0.02-3.73).
- Endovascular revascularization had lower patency and more minor amputations but similar major amputation rates and lower in-hospital mortality compared to open surgery.
Conclusions:
- PAD interventions are centralized in complex hospitals, exhibiting considerable treatment variability.
- Hospital variability in revascularization techniques did not appear to affect leg salvage rates.
- Both endovascular and surgical revascularization resulted in comparable rates of major amputations.
Background:
Indications for the revascularization treatment of peripheral arterial disease (PAD) generate much discussion, and practice varies significantly among hospitals. This study looked at patients with PAD admitted to all hospitals of the Catalan Health Service and analyzed patterns of revascularization techniques with subsequent amputation procedures.
Methods:
We used the clinical-administrative registry of admissions of all patients in the hospitals of Catalonia, north-east Spain, between 2009 and 2014. We analyzed the clinical course of patients admitted with PAD throughout their successive hospital admissions. Variability between hospitals was described for the revascularization techniques and amputations performed. Endovascular outcomes were compared with those from open surgery.
Results:
Annually, there were 9,828 admissions with PAD and 631 major amputations. Eight hospitals accounted for 52% of all admissions, and endovascular techniques occurred predominantly in high-tech, high-resolution or reference hospitals. The ratio of admissions involving endovascular techniques/open surgery varied from 0.02 to 3.73 according to the hospital, and had a correlation of -0.175 (P=0.447) with the percentage of performed major amputations and of 0.122 (P=0.598) ratio of minor / major amputations. At the end of the 6 studied years, endovascular revascularization resulted in lower patency and more minor amputations than open surgery, but had the same percentage of major amputations (10.3% vs. 10.7%, P=0.526) and lower in-hospital mortality (7.1% vs. 9.5%, P<0.0001).
Conclusions:
Interventions of PAD are centralized in complex hospitals and have an important variability depending on the treating hospital. Hospital variability in revascularization techniques seems to have no impact on leg salvage. Endovascular and surgical revascularization would result in similar percentages of major amputations.
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