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Updated: Jan 27, 2026

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Factors associated with opioid use after endoscopic sinus surgery.
Milap D Raikundalia1, Tracy Z Cheng2, Tracy Truong3
1Division of Head and Neck Surgery and Communication Sciences, Department of Surgery, Duke University, Durham, North Carolina.
Responsible opioid prescribing is crucial. This study found that younger patients and those undergoing septoplasty after functional endoscopic sinus surgery (FESS) used more opioid pain medication.
Area of Science:
- Otolaryngology
- Pain Management
- Opioid Stewardship
Background:
- The opioid epidemic necessitates responsible prescribing of postoperative pain medications.
- Understanding factors influencing opioid use after surgery is essential for effective pain management and addiction prevention.
Purpose of the Study:
- To identify clinical factors associated with opioid consumption following functional endoscopic sinus surgery (FESS).
Main Methods:
- A retrospective study analyzed medical records of 136 patients who underwent FESS.
- Opioid usage was quantified at the first postoperative visit.
- Univariate and multivariable analyses identified predictors of opioid use, excluding patients with prior opioid use.
Main Results:
- The majority of patients (78%) used five or fewer opioid tablets in the first postoperative week.
- Younger age (OR 0.96) and concurrent septoplasty (OR 4.84) were significantly associated with higher opioid usage (>5 tablets).
- Factors like gender, extent of surgery, revision status, polyp presence, and cystic fibrosis did not show significant variation in opioid use.
Conclusions:
- Most patients undergoing FESS do not require substantial opioid pain relief postoperatively.
- Younger age and the performance of septoplasty are key factors predicting increased opioid consumption.
- Identifying these predictors aids surgeons in optimizing opioid prescribing and patient counseling.
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