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How Effective Is Pulse Arrival Time for Evaluating Blood Pressure? Challenges and Recommendations from a Study Using

Yongbo Liang1, Derek Abbott2,3, Newton Howard4,5

  • 1School of Electrical and Computer Engineering, University of British Columbia, Vancouver BC V6T 1Z4, Canada. liangyongbo001@gmail.com.

Journal of Clinical Medicine
|March 14, 2019
PubMed

Insights

Investigating pulse arrival time (PAT) in the MIMIC database reveals synchronization errors, impacting blood pressure (BP) evaluation. Correcting these errors is crucial for accurate BP monitoring using cuffless methods.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Medical Informatics

Background:

  • Cardiovascular disease (CVD) is a leading global cause of mortality.
  • Accurate blood pressure (BP) monitoring is vital for CVD prevention and management.
  • Cuffless BP measurement techniques, often based on pulse arrival time (PAT), offer potential advantages over traditional methods.

Purpose of the Study:

  • To investigate the accuracy of pulse arrival time (PAT) calculations within the Medical Information Mart for Intensive Care (MIMIC) database.
  • To assess the impact of potential signal synchronization errors in the MIMIC database on blood pressure (BP) evaluation.
  • To determine the utility of the MIMIC database for research into cuffless BP monitoring.

Main Methods:

  • Analysis of pulse arrival time (PAT) intervals using data from the Medical Information Mart for Intensive Care (MIMIC) database.
  • Evaluation of the common assumption of signal synchronization among researchers using the MIMIC database.
  • Assessment of the calculated PAT intervals for their effectiveness in blood pressure (BP) assessment.

Main Results:

  • Identified erroneous assumptions regarding signal synchronization in the MIMIC database among researchers.
  • Demonstrated that these synchronization errors can affect the calculation and utility of pulse arrival time (PAT) intervals.
  • Highlighted the implications of these findings for the accurate use of the MIMIC database in blood pressure (BP) evaluation studies.

Conclusions:

  • The MIMIC database contains signal synchronization issues that must be addressed for accurate pulse arrival time (PAT) analysis.
  • Future research utilizing the MIMIC database for blood pressure (BP) evaluation requires careful consideration of these synchronization errors.
  • Findings are critical for advancing the development and validation of cuffless blood pressure (BP) monitoring technologies.

Keywords:
blood pressure monitoringdigital medicineglobal healthhypertension assessmenthypertension evaluationpulse arrival timepulse morphologypulse oximeterwearable devices

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