Related Experiment Video
Updated: Jan 27, 2026

P50 Sensory Gating in Infants
Published on: December 26, 2013
Sex as a Moderating Factor in the Relationship Between Hippocampal Volume and Sensory Gating in Patients With
Wei-Lieh Huang1,2,3,4, Chao-Yu Liu1,3, Hon-Man Liu5
11 Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, Yunlin.
Abstract:
Building on the knowledge of sex differences in auditory sensory gating in schizophrenia and hippocampal involvement in sensory gating, this study aimed to investigate sex as a potential moderator of the association between hippocampal volume and P50 in schizophrenia. Auditory P50 gating and hippocampal volume were measured in 16 male and 15 female patients with schizophrenia. The correlations between hippocampal volume and P50 were analyzed in males and females separately, corrected for potential confounders, including age, duration of illness, and antipsychotic medication. Different associative patterns of hippocampal volume with P50 gating ratio and with P50 difference were found by sex. The results suggest sex may play a role in the physiology of sensory gating.
Related Concept Videos
Schizophrenia
Factors Affecting Protein-Drug Binding: Patient-Related Factors
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
What is a Sensory System?
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Relationship Formation
Psychological and Sociocultural Causes of Schizophrenia

