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Updated: Jan 27, 2026

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[Classification and treatment of itch].

Hjalte H Andersen1, Jesper Elberling

  • 1jelberling@dadlnet.dk.

Ugeskrift for Laeger
|March 14, 2019
PubMed
Summary

Chronic itch is a distressing symptom linked to various conditions. This review offers a clinical approach to classifying itch and presents antipruritic treatments for major itch causes.

Area of Science:

  • Dermatology
  • Neurology
  • Internal Medicine

Background:

  • Chronic itch is a prevalent and distressing symptom.
  • It is associated with diverse cutaneous, neuropathic, and systemic diseases.
  • Understanding itch transmission has advanced antipruritic treatment strategies.

Purpose of the Study:

  • To present a rational, clinically based approach to categorizing chronic itch conditions.
  • To summarize antipruritic treatment options for major etiological itch subcategories.
  • To utilize the International Forum for the Study of Itch 2007 classification system.

Main Methods:

  • Review of current understanding of itch transmission.
  • Application of the International Forum for the Study of Itch 2007 classification.

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  • Categorization of chronic itch conditions based on etiology.
  • Summary of available antipruritic treatments.
  • Main Results:

    • A clinically based approach to categorizing chronic itch is presented.
    • Four major etiological subcategories of chronic itch are identified.
    • Antipruritic treatment options are detailed for each subcategory.

    Conclusions:

    • Accurate diagnosis of chronic itch remains crucial.
    • A systematic approach to classifying itch aids in treatment selection.
    • Targeted antipruritic therapies can be guided by etiological categorization.