Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Fluid Mosaic Model01:34

The Fluid Mosaic Model

177.7K
The fluid mosaic model was first proposed as a visual representation of research observations. The model comprises the composition and dynamics of membranes and serves as a foundation for future membrane-related studies. The model depicts the structure of the plasma membrane with a variety of components, which include phospholipids, proteins, and carbohydrates. These integral molecules are loosely bound, defining the cell’s border and providing fluidity for optimal function.
177.7K
Gene Therapy00:59

Gene Therapy

27.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.6K
Accelerating Fluids01:17

Accelerating Fluids

2.3K
When a fluid is in constant acceleration, the pressure and buoyant force equations are modified. Suppose a beaker is placed in an elevator accelerating upward with a constant acceleration, a. In the beaker, assume there is a thin cylinder of height h with an infinitesimal cross-sectional area, ΔS.
The motion of the liquid within this infinitesimal cylinder is considered to obtain the pressure difference. Three vertical forces act on this liquid:
2.3K
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

5.7K
Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain....
5.7K
Fluid Pressure01:14

Fluid Pressure

1.2K
In mechanical engineering, fluid pressure plays a critical role in designing systems that utilize liquid flow, such as hydraulic systems, pumps, and valves. When designing these systems, engineers must ensure they can withstand the forces created by fluid pressure to avoid damage or failure.
According to Pascal's law, a fluid at rest will generate equal pressure in all directions. This pressure is measured as a force per unit area, and its magnitude depends on the fluid's specific...
1.2K
Characteristics of Fluids01:31

Characteristics of Fluids

1.0K
Fluids differ from solids primarily in their molecular structure and stress response. Solids have tightly packed molecules with strong intermolecular forces, maintaining their shape and resisting deformation. In contrast, fluids have molecules spaced farther apart with weaker forces, allowing them to flow and deform easily.
Fluids, which include both liquids and gases, are substances that deform continuously under shearing stress. For example, water and oil are liquids with molecules that can...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interdisciplinary perspectives on multi-risk anticipatory action.

iScience·2026
Same author

Individualised duration of antibiotic treatment in culture-negative early-onset sepsis in late-preterm and term-born neonates in Denmark (DURATION): a multicentre, open-label, randomised, controlled, non-inferiority trial.

The Lancet. Child & adolescent health·2026
Same author

Sepsis and Antibiotics in Extremely Preterm Infants: Early Empirical Treatment Was Common, While Late-Onset Sepsis Accounted for Most Cases and Antibiotic Use.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

Academic achievements after childhood meningitis: a nationwide, population-based cohort study.

Infectious diseases (London, England)·2026
Same author

Retinal Neurophysiological Parameters in Young Patients With Type 1 Diabetes.

Investigative ophthalmology & visual science·2026
Same author

Early discontinuation of empirical antibiotics versus extended treatment in children with cancer and high-risk febrile neutropenia in Denmark: an open-label, randomised controlled trial.

The Lancet. Child & adolescent health·2026

Related Experiment Video

Updated: Jan 27, 2026

Intravenous Injections in Neonatal Mice
05:17

Intravenous Injections in Neonatal Mice

Published on: November 11, 2014

61.3K

[Intravenous fluid therapy in children].

Aurora Undlien1, Maren Rytter, Christian Overgaard-Steensen

  • 1Ulrikka@dadlnet.dk.

Ugeskrift for Laeger
|March 14, 2019
PubMed
Summary

Danish hospitals commonly use hypotonic fluids for children, risking hyponatremia. Isotonic fluids are recommended to prevent severe neurological complications in pediatric patients.

More Related Videos

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
06:43

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

Published on: October 9, 2018

10.2K
Optimized Intravenous Injection in Adult Zebrafish
05:17

Optimized Intravenous Injection in Adult Zebrafish

Published on: December 20, 2024

2.1K

Related Experiment Videos

Last Updated: Jan 27, 2026

Intravenous Injections in Neonatal Mice
05:17

Intravenous Injections in Neonatal Mice

Published on: November 11, 2014

61.3K
Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
06:43

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

Published on: October 9, 2018

10.2K
Optimized Intravenous Injection in Adult Zebrafish
05:17

Optimized Intravenous Injection in Adult Zebrafish

Published on: December 20, 2024

2.1K

Area of Science:

  • Pediatric Medicine
  • Clinical Practice
  • Fluid Management

Background:

  • Danish hospitals routinely prescribe hypotonic maintenance fluids (20-40 mmol/l sodium) for pediatric patients with reduced intake.
  • Evidence indicates a link between hypotonic fluids and potentially fatal hyponatremia in children.
  • This practice poses a significant risk of neurological damage.

Purpose of the Study:

  • To recommend a shift in fluid management protocols for pediatric patients.
  • To advocate for the availability of isotonic maintenance fluids in all Danish hospitals.
  • To mitigate the risk of hyponatremia and associated neurological complications.

Main Methods:

  • Review of existing evidence on fluid therapy in pediatric care.
  • Analysis of the risks associated with hypotonic fluid administration.
  • Formulation of recommendations for standardized isotonic fluid use.

Main Results:

  • Hypotonic maintenance fluids are associated with increased risk of hyponatremia in children.
  • Isotonic solutions (140-154 mmol/l sodium, 5% glucose) are identified as a safer alternative.
  • Addition of potassium (20 mmol/l) may be considered for specific pediatric needs.

Conclusions:

  • Standardizing the use of isotonic maintenance fluids is crucial for pediatric patient safety.
  • Implementation of these fluids can prevent hyponatremia and neurological sequelae.
  • A change in practice is urgently needed in Danish pediatric departments.