Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Uterus and Cervix01:18

Uterus and Cervix

The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs of...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Observational Study Profiling the Immune Microenvironment of Pregnancy-associated Melanoma.

The American Journal of dermatopathology·2026
Same author

Novel ultrasound-guided flags assisted WalKing block for enhanced recovery after surgery (FAWKES) in three dogs undergoing tibial plateau levelling osteotomy.

Veterinary anaesthesia and analgesia·2026
Same author

Diagnosis and management of nipple-areolar complex conditions in postmenopausal women: a retrospective study highlighting multidisciplinary care needs.

International journal of women's dermatology·2026
Same author

Anti-MDA-5 dermatomyositis with tumid lupus-like lesions.

JAAD case reports·2025
Same author

Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.

Nature communications·2024
Same author

Protocol for the generation of cultured cortical brain organoid slices.

STAR protocols·2024

Related Experiment Video

Updated: Jul 14, 2026

Isolation of Human Umbilical Vein Endothelial Cells HUVEC
09:19

Isolation of Human Umbilical Vein Endothelial Cells HUVEC

Published on: April 28, 2007

32.8K

Umbilical condyloma lata.

Claire Alexanian, Stephanie Le, Chelsea Ma

  • 1Department of Dermatology, University of California, Davis Medical Center, Sacramento, California. dtartar@ucdavis.edu.

Dermatology Online Journal
|March 14, 2019
PubMed
Summary

Condyloma lata, a syphilis symptom, typically affects the anogenital region. This case highlights an unusual umbilical presentation, emphasizing the need for broad diagnostic considerations.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Syphilology

Background:

  • Condyloma lata are a common cutaneous manifestation of secondary syphilis.
  • They typically present as verrucous papules and plaques.
  • The anogenital area is the most frequent site of involvement.

Observation:

  • Umbilical involvement with condyloma lata is exceptionally rare.
  • This report details a unique case of condyloma lata manifesting on the umbilicus.
  • The patient's presentation deviated from the typical clinical picture.

Findings:

  • The case underscores the importance of considering syphilis in differential diagnoses, even with atypical presentations.
  • Prompt diagnosis relies on thorough patient history, physical examination, and laboratory tests.

More Related Videos

Isolation of Precursor B-cell Subsets from Umbilical Cord Blood
14:06

Isolation of Precursor B-cell Subsets from Umbilical Cord Blood

Published on: April 16, 2013

18.7K
Author Spotlight: Advancements in Stem Cell-Derived Vascularized Organoids and Optimized Isolation of Wharton's Jelly for Enhanced MSC Production
04:47

Author Spotlight: Advancements in Stem Cell-Derived Vascularized Organoids and Optimized Isolation of Wharton's Jelly for Enhanced MSC Production

Published on: July 5, 2024

4.1K

Related Experiment Videos

Last Updated: Jul 14, 2026

Isolation of Human Umbilical Vein Endothelial Cells HUVEC
09:19

Isolation of Human Umbilical Vein Endothelial Cells HUVEC

Published on: April 28, 2007

32.8K
Isolation of Precursor B-cell Subsets from Umbilical Cord Blood
14:06

Isolation of Precursor B-cell Subsets from Umbilical Cord Blood

Published on: April 16, 2013

18.7K
Author Spotlight: Advancements in Stem Cell-Derived Vascularized Organoids and Optimized Isolation of Wharton's Jelly for Enhanced MSC Production
04:47

Author Spotlight: Advancements in Stem Cell-Derived Vascularized Organoids and Optimized Isolation of Wharton's Jelly for Enhanced MSC Production

Published on: July 5, 2024

4.1K
  • Recognizing unusual manifestations aids in timely and accurate diagnosis of secondary syphilis.

    • Implications:

    • Clinicians should maintain a high index of suspicion for syphilis when encountering unusual cutaneous lesions.
    • Awareness of rare presentations like umbilical condyloma lata can prevent diagnostic delays.
    • This case contributes to the understanding of the varied clinical spectrum of secondary syphilis.