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Glypican-3 expression in malignant small round cell tumors

Yuichi Shibui1, Kina Miyoshi2, Kenichi Kohashi1

  • 1Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

Oncology Letters
|March 15, 2019
PubMed
Summary

Glypican-3 (GPC3) shows focal expression in pediatric rhabdomyosarcomas, aiding differential diagnosis. GPC3 overexpression may help distinguish rhabdomyosarcomas from Ewing sarcomas and desmoplastic small round cell tumors.

Keywords:
Ewing sarcomadesmoplastic small round cell tumorglypican-3oncofetal proteinrhabdomyosarcomasmall round cell tumors

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