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Liraglutide-induced Acute Gastroparesis
Puja Rai1, Mahmoud Y Madi1, Aaron Dickstein2
1Internal Medicine, Tufts Medical Center, Boston, USA.
Cureus
|March 15, 2019
Summary
Liraglutide, a type 2 diabetes medication, can cause acute gastroparesis. Discontinuing the drug and using conservative treatments resolved symptoms in a 52-year-old patient.
Area of Science:
- Endocrinology
- Gastroenterology
Background:
- Liraglutide is a glucagon-like peptide-1 receptor agonist used for type 2 diabetes management.
- Gastroparesis is a condition characterized by delayed gastric emptying.
Observation:
- A 52-year-old male with type 2 diabetes presented with symptoms of gastric outlet obstruction.
- The patient was on liraglutide therapy for his diabetes.
Findings:
- The patient developed acute gastroparesis, a potential side effect of liraglutide.
- Symptoms resolved with conservative management, including gastric suctioning, antiemetics, prokinetics, and liraglutide discontinuation.
Implications:
- Drug-induced gastroparesis should be considered in patients with unexplained upper abdominal symptoms.
- Early recognition and management can lead to symptom resolution and prevent complications.
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