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Brain-Gut Therapies for Pediatric Functional Gastrointestinal Disorders and Inflammatory Bowel Disease

Hannibal Person1, Laurie Keefer2

  • 1Department of Pediatrics, Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, One Gustave Place, Box 1656, New York, NY, 10029, USA. hannibal.person@mssm.edu.

Current Gastroenterology Reports
|March 15, 2019
PubMed

Insights

Brain-gut therapies (BGT) show promise for pediatric functional gastrointestinal disorders (FGID) and inflammatory bowel disease (IBD). Cognitive behavioral therapy and hypnotherapy are well-supported, with integrative approaches offering the most patient benefit.

Area of Science:

  • Pediatric Gastroenterology
  • Psychosomatic Medicine
  • Neurogastroenterology

Background:

  • Functional gastrointestinal disorders (FGID) and inflammatory bowel disease (IBD) in children often involve psychological factors.
  • Brain-gut therapies (BGT) offer a potential avenue for managing these complex conditions.
  • Understanding the interplay between the brain and gut is crucial for effective pediatric care.

Purpose of the Study:

  • To review current knowledge on BGT for pediatric FGID and IBD.
  • To examine the evidence base for various BGT modalities.
  • To discuss the integration of BGT into clinical practice.

Main Methods:

  • Literature review of BGT in pediatric FGID and IBD.
  • Analysis of evidence supporting therapies like CBT, HT, MBT, and EBT.
  • Discussion of psychopathology addressed by BGT.

Main Results:

  • Cognitive behavioral therapy (CBT), hypnotherapy (HT), mindfulness-based therapy (MBT), and exposure-based therapy (EBT) have the strongest evidence in pediatric FGID.
  • Evidence for BGT in pediatric IBD is less robust but growing, acknowledging comorbid psychological factors.
  • Integrative BGT strategies involving multidisciplinary collaboration show significant potential.

Conclusions:

  • BGT, particularly CBT and HT, are valuable tools for pediatric FGID and increasingly for IBD.
  • Addressing psychological factors is key to successful BGT implementation in pediatric GI care.
  • Integrated, multidisciplinary BGT approaches can optimize patient outcomes.
Abstract

Keywords:
Brain-gut therapiesCognitive behavioral therapyFunctional gastrointestinal disordersInflammatory bowel diseaseIrritable bowel syndromePediatricsPsychological treatments

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