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Updated: Jan 27, 2026

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Electrocardiographic parameters of Sapajus libidinosus (SPIX, 1823) after chemical immobilization with
Ana Yasha F de La Salles1, Jéssica K Andrade2, Khelven K A Lemos3
1Programa de Pós-Graduação em Medicina Veterinária, Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Patos, Paraíba, Brasil.
Background:
Tiletamine-zolazepam is a widely used as an alternative chemical immobilization method in non-human primates, with a safe application pathway and necessary relaxation. In order to determine the electrocardiographic parameters of Sapajus libidinosus after intramuscular tiletamine-zolazepam administration at the dose of 5 mg/kg, nine animals were submitted to anesthesia.
Methods:
The interpretation of the electrocardiogram determined: heart rate in bpm and heart rhythm, P wave, P-R interval, R wave, QRS complex, T wave, Q-T interval, corrected QT interval and electrical axis. The mean HR was 206 ± 32 bpm.
Results:
The majority of the monkeys showed normal sinus rhythm, but one animal showed sinus tachycardia. The most commonly observed electrical axis was between +30° and +90°. Two animals presented bigger alterations in the tracing such as low amplitude QRS and T wave bigger than 1/4 of the R wave.
Conclusions:
The administration of tiletamine-zolazepam was safe and efficacious, with minimal cardiovascular effects.
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