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Engineering Antiviral Agents via Surface Plasmon Resonance
Published on: June 14, 2022
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Recent Advances in Surface Plasmon Resonance Imaging Sensors
Dongping Wang1, Jacky Fong Chuen Loo2,3, Jiajie Chen4
1Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong, China. lilianadpwang@gmail.com.
Sensors (Basel, Switzerland)
|March 16, 2019
Summary
Surface Plasmon Resonance (SPR) imaging offers a high-throughput, label-free method for analyzing biomolecular interactions. This review highlights recent advancements in SPR imaging instrumentation and its applications in molecular sensing, healthcare, and environmental screening.
Area of Science:
- Biotechnology
- Analytical Chemistry
- Biosensing
Background:
- Surface Plasmon Resonance (SPR) sensors are crucial for studying biomolecular binding kinetics.
- Existing SPR instruments typically use single- or few-channel configurations.
- The demand for high-throughput screening necessitates advanced SPR technologies.
Purpose of the Study:
- To provide a concise summary of recent advances in SPR imaging (SPRi).
- To focus on practical instrumentation designs for SPRi.
- To discuss SPRi applications in molecular sensing, healthcare, and environmental screening.
Main Methods:
- Review of recent literature on SPR imaging instrumentation.
- Analysis of SPRi sensor array designs.
- Evaluation of SPRi biosensing applications.
Main Results:
- SPRi enables high-throughput, real-time, and label-free detection.
- Recent instrumentation designs focus on 2-D sensor arrays for massive-scale analysis.
- SPRi shows significant potential in diverse applications.
Conclusions:
- SPRi is a rapidly advancing technology for large-scale biomolecular interaction analysis.
- Practical instrumentation and diverse applications are key areas of recent progress.
- SPRi is poised to impact drug discovery, healthcare diagnostics, and environmental monitoring.
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