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Abdominal Ectopic Thyroid Tissue: The Man From Istanbul.

Michela Campora1, Chiara Trambaiolo Antonelli1, Luca Valle1

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Thyroid ectopia, or thyroid tissue in unusual locations, is rare below the diaphragm. This study reports the first case of ectopic thyroid tissue found in the periappendiceal fat.

Keywords:
abdomenappendixectopic thyroidimmunohistochemistrypitfall in pathology

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Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Embryology

Background:

  • Thyroid ectopia is defined as the presence of normal thyroid tissue outside its usual anatomical location.
  • Ectopic thyroid tissue is typically found along the thyroglossal duct pathway, from the foramen cecum to the base of the tongue.
  • Locations below the diaphragm are exceptionally rare.

Observation:

  • This article describes a unique case of thyroid tissue identified within the periappendiceal fat.
  • The ectopic thyroid tissue exhibited normal parenchyma and preserved thyroid marker immunoreactivity, consistent with functional thyroid tissue.

Findings:

  • This represents the first documented instance of thyroid tissue occurring in the periappendiceal region.
  • The presence of ectopic thyroid tissue in this location challenges current understanding of embryological development and migration patterns.

Implications:

  • This case expands the known spectrum of thyroid ectopia and its potential locations.
  • Further research into the embryogenesis of ectopic thyroid tissue may provide insights into developmental anomalies.
  • Understanding these rare presentations is crucial for accurate diagnosis and management in surgical and endocrine settings.