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Experience of a fungal infection after cardiac surgery

L Vicente-Martínez1, R Vicente-Guillen1, E Calabuig2

  • 1Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Hospital Universitario y Politécnico La Fe, Valencia, España.

Revista Espanola De Anestesiologia Y Reanimacion
|March 16, 2019
PubMed
Abstract

Insights

Multiple blood transfusions significantly increase the risk of invasive candidiasis in cardiac surgery patients. Hospitals should implement surveillance for fungal infections in high-risk individuals.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Critical Care Medicine

Background:

  • Cardiac surgery patients face post-operative complications, including invasive fungal infections.
  • Invasive candidiasis is a serious concern in post-cardiac surgery care.

Purpose of the Study:

  • To determine the incidence, severity, and risk factors of invasive candidiasis in cardiac surgery patients.
  • To investigate the association between factors like multiple transfusions and extracorporeal circulation time with invasive candidiasis.

Main Methods:

  • Prospective analysis of 669 patients undergoing scheduled cardiac surgery.
  • Data collected from April 2016 to December 2017, with control cultures from the Surgical Intensive Care Unit.

Main Results:

  • Invasive candidiasis incidence was 2.69%, confirmed in 1.79% of cases.
  • Candida auris was the most frequent species; mortality was 11% (immediate post-op) and 22% (30-day).
  • Multiple transfusions showed a strong association (OR 15.86) with invasive candidiasis.

Conclusions:

  • Multiple transfusions are a significant risk factor for invasive candidiasis post-cardiac surgery.
  • Hospitals with high candidiasis rates need surveillance for at-risk patients.
  • Early identification and management of risk factors are crucial for improving outcomes.
Keywords:
CandidiasisCardiac surgeryCirculación extracorpóreaCirugía cardiacaComplicaciones postoperatoriasExtracorporeal circulationFungal infectionInfección fúngicaMultiple transfusionsPolitransfusiónPost-operative complications

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