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Mechanical Thrombectomy Outcome Predictors in Stroke Patients with M2 Occlusion: A Single-Center Retrospective Study

Lin Jiang1, Wen-Qing Xia1, Huan Huang1

  • 1Department of Neurology, Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

World Neurosurgery
|March 16, 2019
PubMed
Abstract

Insights

Mechanical thrombectomy (MT) is safe and effective for acute ischemic stroke patients with middle cerebral artery (MCA) M2 segment occlusions. Higher baseline NIHSS scores predict poorer outcomes after MT for these strokes.

Area of Science:

  • Neurology
  • Interventional Neurology
  • Stroke Medicine

Background:

  • Mechanical thrombectomy (MT) is established for large-vessel occlusion ischemic stroke.
  • Its efficacy in middle cerebral artery (MCA) M2 segment occlusions remains less clear.
  • Understanding outcomes and predictors for M2 occlusions is crucial.

Purpose of the Study:

  • To evaluate the safety and effectiveness of MT for acute MCA M2 segment occlusions.
  • To identify clinical predictors of outcomes in these patients.
  • To assess the feasibility of extrapolating MT benefits to M2 occlusions.

Main Methods:

  • Single-center retrospective analysis of consecutive patients.
  • Inclusion criteria: acute MCA M2 segment occlusion treated with stent retriever MT.
  • Correlation of clinical/radiographic outcomes with patient characteristics.

Main Results:

  • 37 patients analyzed (median NIHSS 15, mean age 74, 48.6% women).
  • Good clinical outcome (mRS ≤2) at 3 months achieved in 48.6%.
  • Baseline NIHSS score predicted clinical outcomes (P=0.015, OR 1.63).

Conclusions:

  • MT for MCA M2 occlusions is safe and effective.
  • Baseline NIHSS is a significant predictor of outcomes.
  • Supports MT as a viable treatment for M2 occlusions.
Keywords:
Middle cerebral arteryStrokeThrombectomy

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