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Related Concept Videos

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

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Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
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Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

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Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
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Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

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Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
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Chemical Reactions in Aqueous Solutions03:03

Chemical Reactions in Aqueous Solutions

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Chemical substances interact in many different ways. Certain chemical reactions exhibit common patterns of reactivity. Due to the vast number of chemical reactions, it becomes necessary to classify them based on the observed patterns of interaction.
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Aqueous Solutions and Heats of Hydration02:42

Aqueous Solutions and Heats of Hydration

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Water and other polar molecules are attracted to ions. The electrostatic attraction between an ion and a molecule with a dipole is called an ion-dipole attraction. These attractions play an important role in the dissolution of ionic compounds in water.
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
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Leveling Effect and Non-Aqueous Acid-Base Solutions02:11

Leveling Effect and Non-Aqueous Acid-Base Solutions

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This lesson defines the leveling effect in acidic and basic solutions and its role in aqueous and non-aqueous solutions. It is essential to understand the competing nature of various species in a chemical system.
The Leveling Effect of a Solvent
A generic acid (HA) reacts with the generic base (B-) to yield the corresponding conjugate base (A-) and conjugate acid (HB):
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Related Experiment Video

Updated: Jan 27, 2026

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
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Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

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Aqueous olefin metathesis: recent developments and applications.

Valerio Sabatino1, Thomas R Ward1

  • 1Department of Chemistry, University of Basel, Building 1096, Mattenstraße 24a, Biopark Rosental, 4058, Basel, Switzerland.

Beilstein Journal of Organic Chemistry
|March 16, 2019
PubMed
Summary
This summary is machine-generated.

Aqueous olefin metathesis reactions offer a sustainable and biocompatible alternative for forming carbon-carbon double bonds. This review highlights advancements in water-based metathesis and its use in chemical biology.

Keywords:
aqueous catalysisartificial metalloenzymeschemical biologygreen chemistryolefin metathesisruthenium catalystsstapled peptides

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Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
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Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
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Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization
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Area of Science:

  • Organic Chemistry
  • Chemical Biology
  • Polymer Chemistry

Background:

  • Olefin metathesis is a powerful reaction for forming carbon-carbon double bonds.
  • Metathesis reactions are vital in polymer chemistry, drug discovery, and chemical biology.
  • Performing metathesis in water presents challenges but offers sustainability and biocompatibility.

Purpose of the Study:

  • To review progress in aqueous olefin metathesis.
  • To highlight applications of aqueous metathesis in chemical biology.

Main Methods:

  • Literature review of recent advancements in aqueous olefin metathesis.
  • Analysis of catalytic systems and reaction conditions for water-based metathesis.
  • Examination of case studies demonstrating applications in chemical biology.

Main Results:

  • Significant progress has been made in developing catalysts and conditions for olefin metathesis in aqueous media.
  • Aqueous metathesis enables greener synthetic routes and expands the scope of applications in biologically relevant systems.
  • Successful applications in chemical biology demonstrate the utility of water-based reactions.

Conclusions:

  • Aqueous olefin metathesis is a rapidly advancing field with significant potential.
  • The use of water as a solvent enhances sustainability and biocompatibility in organic synthesis.
  • Further development promises broader applications in drug discovery and chemical biology.