Rare Complication of Botox Injection: A Case Report
Abdolreza Rouientan1, Hamidreza Alizadeh Otaghvar2, Hossein Mahmoudvand1
1Department of Plastic and Reconstructive Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
World Journal of Plastic Surgery
|March 16, 2019
Summary
Botulinum toxin (Botox) can cause generalized complications, even when used for cosmetic reasons like hyperhidrosis. A patient experienced severe symptoms after Botox treatment, highlighting the risk of adverse effects.
Area of Science:
- Neurology
- Toxicology
- Bacteriology
Background:
- Botulinum toxin (BTX), commonly known as Botox, is a neurotoxin produced by *Clostridium botulinum*.
- It has diverse therapeutic and cosmetic applications, including treating conditions like hyperhidrosis, cervical dystonia, and chronic migraine.
- While effective, BTX can cause adverse effects due to local or systemic spread.
Observation:
- A 22-year-old male received Botox for axillary hyperhidrosis.
- Generalized complications associated with botulinum toxin appeared two weeks post-treatment.
- The patient presented with symptoms indicative of systemic botulism.
Findings:
- The case highlights the potential for severe, generalized adverse effects from therapeutic or cosmetic Botox injections.
- Symptoms appeared two weeks after treatment for axillary hyperhidrosis.
- Pyridostigmine was administered and found to alleviate the patient's symptoms.
Implications:
- This case underscores the importance of recognizing and managing potential systemic complications of botulinum toxin.
- Awareness of these risks is crucial for clinicians administering Botox for any indication.
- Prompt symptomatic treatment, such as with pyridostigmine, may be beneficial in managing adverse reactions.
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