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Related Experiment Video

Updated: Jan 27, 2026

Examining Local Network Processing using Multi-contact Laminar Electrode Recording
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Consent2Share: an integrated broad consenting process for re-contacting potential study subjects.

R Peter Iafrate1, Gloria P Lipori2, Christopher A Harle3

  • 1Institutional Review Board, University of Florida, Gainesville, Florida, United States.

Journal of Clinical and Translational Research
|March 16, 2019
PubMed
Summary

Researchers developed an electronic system to streamline patient consent for clinical studies. This Consent2Share process efficiently identifies and contacts eligible participants, overcoming previous procedural hurdles and improving research subject accrual.

Keywords:
clinical research studiesconsentcontact registrieselectronic consentglobal consentrecruitmentresearch subjects

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Area of Science:

  • Clinical research methodology
  • Health informatics
  • Patient recruitment strategies

Background:

  • Recruiting sufficient participants is a major challenge in clinical research.
  • Privacy regulations complicate the identification of eligible study subjects.
  • Existing methods for obtaining research consent are often inefficient.

Purpose of the Study:

  • To develop and evaluate an electronic process for obtaining patient consent for research participation.
  • To improve the efficiency of identifying and recruiting subjects for clinical studies.
  • To create a model for broad research consent procedures compliant with evolving regulations.

Main Methods:

  • An interdisciplinary team developed an electronic consent method integrated with Electronic Medical Records (EHR).
  • Patients attending subspecialty clinics were asked to consent to EHR review for research eligibility.
  • Consenting patients were contacted for potential research study involvement if they met criteria.

Main Results:

  • An initial paper-based method had high consent rates but faced scalability issues.
  • The revised electronic Consent2Share process enrolled nearly 28,000 patients over 3 years.
  • The system supported 20 Institutional Review Board (IRB)-approved protocols.

Conclusions:

  • A multidisciplinary approach is crucial for developing effective electronic consent systems.
  • Integrated electronic consent processes facilitate investigator access to potential study subjects.
  • The Consent2Share model offers an efficient way to enhance research subject accrual and comply with regulatory changes.