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Absolute Quantification of Plasma MicroRNA Levels in Cynomolgus Monkeys, Using Quantitative Real-time Reverse Transcription PCR
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An LC-MS/MS approach to assess total and free protein target in the serum of cynomolgus monkey

Hongmei Cao1, Guodong Zhang1, Kristina Ciociola1

  • 1Bioanalytical & Biomarker Development, Takeda Pharmaceuticals International Co., 125 Binney Street, Cambridge, MA 02142, USA.

Bioanalysis
|March 16, 2019
PubMed
Abstract

Keywords:
LC–MS/MScomplement component C5immunodepletionprotein Aquasi-equilibriumtarget engagementtotal and free target

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