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Updated: Jan 27, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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The Hypertensive Headache: a Review

Karissa N Arca1, Rashmi B Halker Singh2

  • 1Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ, 85259, USA. Arca.Karissa@mayo.edu.

Current Pain and Headache Reports
|March 16, 2019
PubMed

Insights

Headaches linked to high blood pressure (hypertension) are often secondary to elevated readings. Recent research explores cellular mechanisms and blood-brain barrier disruption in hypertensive headaches, including during pregnancy.

Area of Science:

  • Neurology
  • Cardiology
  • Nephrology

Background:

  • Headache is a common symptom with diverse etiologies.
  • Arterial hypertension is a significant public health concern.
  • Understanding secondary headaches is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To review common and uncommon causes of headache attributed to arterial hypertension.
  • To update on recent findings regarding hypertensive headaches.
  • To focus on secondary headache disorders associated with elevated blood pressure.

Main Methods:

  • Literature review of common causes of headache in hypertension.
  • Analysis of recent studies and case reports on hypertensive headache pathophysiology.
  • Discussion of trends in hypertensive headache, including during pregnancy.

Main Results:

  • Hypertensive headaches are primarily secondary to elevated blood pressure.
  • Pathophysiology involves cellular-level changes and blood-brain barrier disruption.
  • Carotid revascularization syndrome is a related condition with proposed criteria.

Conclusions:

  • Hypertensive headaches require careful evaluation to identify underlying causes.
  • The relationship between chronic hypertension and headache, especially migraine, remains complex.
  • Further research is needed to clarify the multifactorial links between hypertension and headache disorders.
Abstract

Keywords:
ArterialAutoregulationBlood pressureHeadacheHypertensionSecondary headache

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