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Updated: Jan 27, 2026

The Mouse Cremaster Muscle Preparation for Intravital Imaging of the Microcirculation
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Preload Dependence Is Associated with Reduced Sublingual Microcirculation during Major Abdominal Surgery

Karim Bouattour1, Jean-Louis Teboul, Laurent Varin

  • 1From the University Hospitals of Paris-Sud, Assistance Publique Des Hôpitaux De Paris, Critical Care and Anesthesia Department, Antoine Béclère Hospital, Clamart, France (K.B.) University Hospitals of Paris-Sud, Assistance Publique Des Hôpitaux De Paris, Medical Intensive Care Unit (J.-L.T.) Critical Care and Anesthesia Department (L.V., J.D.), Bicêtre Hospital, Le Kremlin Bicêtre, France Clinical Research Unit, UMR 942, Lariboisiere University Hospital, Paris, France (E.V.).

Anesthesiology
|March 16, 2019
PubMed
Summary

During major abdominal surgery, preload dependence impairs sublingual microcirculation. Fluid administration effectively restores microvascular perfusion, improving patient outcomes in critical care settings.

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