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Updated: Jan 27, 2026

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Human Heart Explant-Derived Extracellular Vesicles: Characterization and Effects on the In Vitro Recellularization of

Amanda Leitolis1, Paula Hansen Suss2, João Gabriel Roderjan3

  • 1Laboratory of Basic Biology of Stem Cells, Carlos Chagas Institute, Fiocruz-Paraná, Curitiba 81350-010, Brazil. aleitolis@gmail.com.

International Journal of Molecular Sciences
|March 17, 2019
PubMed
Summary

Human heart-derived extracellular vesicles (hH-EVs) show promise for tissue regeneration. These vesicles promote cell proliferation, angiogenesis, and wound healing, aiding in scaffold recellularization.

Keywords:
cardiac regionsextracellular vesicleheart valvehuman heartmesenchymal stromal cellsrecellularizationtissue engineeringtissue explant

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