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Updated: Jan 27, 2026

Determination of Total Lipid and Lipid Classes in Marine Samples
Published on: December 11, 2021
Latest Updates on Lipid Management
Emmanuel Eroume-A Egom1,2, Rebabonye B Pharithi3, Soressa Hesse3
1Department of Clinical Medicine, Education Division, School of Medicine, Trinity College Dublin, Dublin, Ireland. egom@ectrs.ca.
Insights
Atherosclerotic cardiovascular disease (ASCVD) remains a global health threat. This review highlights current lipid management strategies and cholesterol-lowering agents to improve ASCVD prevention and treatment outcomes.
Area of Science:
- Cardiology
- Vascular Medicine
- Pharmacology
Background:
- Atherosclerotic cardiovascular disease (ASCVD) is the primary cause of mortality globally.
- Despite proven benefits in primary and secondary prevention, cholesterol management is often suboptimal, with many patients failing to reach target levels.
- Under-treatment of high cholesterol contributes significantly to the ASCVD burden.
Purpose of the Study:
- To provide an updated review of lipid management strategies for ASCVD.
- To emphasize the clinical applications of various cholesterol-lowering drug classes.
- To inform healthcare professionals on optimizing lipid targets for cardiovascular risk reduction.
Main Methods:
- Literature review of recent clinical guidelines and research.
- Analysis of different classes of lipid-lowering therapies.
- Synthesis of evidence on the efficacy and safety of cholesterol management.
Main Results:
- ASCVD necessitates aggressive lipid management for effective prevention.
- Multiple classes of cholesterol-lowering agents are available, each with specific indications and benefits.
- Achieving target lipid levels remains a challenge in clinical practice.
Conclusions:
- Optimizing lipid management is crucial for reducing ASCVD incidence and mortality.
- A comprehensive understanding of available cholesterol-lowering agents is essential for personalized patient care.
- Further efforts are needed to improve treatment adherence and target attainment in patients at risk for ASCVD.
Abstract:
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death worldwide. Despite the clinical long-term and near-term benefits of lowering cholesterol in, respectively, primary and secondary prevention of ASCVD, cholesterol levels remain under-treated, with many patients not achieving their recommended targets. The present article will review the latest updates on lipid management with emphases on the different classes of cholesterol-lowering agents and their clinical uses.
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