Related Experiment Video
Updated: Jan 27, 2026
Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
Published on: January 22, 2022
Serum antimüllerian hormone concentration increases with ovarian endometrioma size
Louis Marcellin1, Pietro Santulli1, Mathilde Bourdon2
1Département de Gynécologie Obsétrique II et Médecine de la Reproduction, Faculté de Médecine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Universitaire Paris Centre (HUPC), Centre Hospitalier Universitaire (CHU) Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Département "Développent, Reproduction et Cancer", INSERM U1016, Institut Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Département "Stress Oxydant, Prolifération Cellulaire et Inflammation", Institut Cochin, INSERM U1016, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Objective:
To examine whether serum antimüllerian hormone (AMH) levels correlate with the size of ovarian endometrioma (OMA).
Design:
An observational cross-sectional study.
Setting:
University hospital.
Patient(S):
Two hundred and sixty-seven nonpregnant women, aged 18-42 years, with no prior history of surgery for endometriosis and a histologically documented ovarian cyst.
Intervention(S):
Surgical management for a benign ovarian cyst.
Main Outcome Measure(S):
Correlation between serum AMH concentration and cyst size according to OMA and non-OMA benign cyst.
Result(S):
Women with OMA were compared with a control group of women who had non-OMA benign ovarian cysts. The AMH assay samples were collected less than a month before the surgery. Between January 2004 and September 2016, 148 women were allocated to the OMA group and 119 to the non-OMA benign cyst group. The AMH concentrations were not statistically significantly different between the two groups (3.7 ± 2.8 ng/mL vs. 4.1 ± 3.3 ng/mL). A multiple linear regression model accounting for potential confounders revealed that the log10 of the serum AMH concentration positively correlated with the log10 of the OMA cyst volume (R2 = 0.23; coefficient = 0.05; 95% CI, 0.007-0.10).
Conclusion(S):
In women no prior history of surgery for endometriosis, serum AMH levels increased with cyst size in cases of OMA.
Related Concept Videos
01:30Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
02:13Types of Hormones
01:21Types of Hormones
Steroids and eicosanoids fall under the category of lipid-soluble hormones. Steroids are derived from cholesterol and feature four interconnected carbon rings with variable side chains. Notable examples include estradiol from ovaries and testosterone from testes, exemplifying the critical roles of these lipid-soluble hormones in reproductive physiology. Eicosanoids, derived...
01:33Hormonal Regulation
01:40Hormonal Regulation
01:56Plant Hormones