Oil toxicity and implications for environmental tolerance in fish

Crude oil and its constituent chemicals are common environmental toxicants in aquatic environments worldwide, and have been the subject of intense research for decades. Importantly, aquatic environments are also the sites of numerous other environmental disturbances that can impact the endemic fauna. While there have been a number of attempts to explore the potential additive and synergistic effects of oil exposure and environmental stressors, many of these efforts have focused on the cumulative effects on typical toxicological endpoints (e.g. survival, growth, reproduction and cellular damage). Fewer studies have investigated the impact that oil exposure may have on the ability of exposed animals to tolerate typically encountered environmental stressors, despite the fact that this is an important consideration when placing oil spills in an ecological context. Here we review the available data and highlight potentially understudied areas relating to how oil exposure may impair organismal responses to common environmental stressors in fishes. We focused on four common environmental stressors in aquatic environments - hypoxia, temperature, salinity and acid-base disturbances - while also considering social stress and impacts on the hypothalamus-pituitary-interrenal axis. Overall, we believe the evidence supports treating the impacts of oil exposure on environmental tolerance as an independent endpoint of toxicity in fishes.