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Updated: Jan 27, 2026

Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
Published on: September 25, 2013
[Use of intravenous and subcutaneous human immunoglobulins]
Béatrice Ramus1, Omar Benbrahim1, Patrick Chérin2
1Service oncologie médicale, centre hospitalier régional d'Orléans, 14, avenue de l'Hôpital, 45067 Orléans, France.
Abstract:
Immunoglobulin preparations are medicines derived from blood used as a replacement therapy for immunodeficiencies or as an immunomodulator. While they are generally well-tolerated, side effects, rarely severe, can nevertheless occur when administered intravenously. They are usually related to an excessive perfusion rate. The recent arrival of safer products administered subcutaneously represents progress in the treatment of patients.
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