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Fat-Covered Islet Transplantation Using Epididymal White Adipose Tissue
Published on: May 25, 2021
Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Stella X Chen1, Ling-Juan Zhang2, Richard L Gallo1
1Department of Dermatology, University of California, San Diego, La Jolla, California, USA.
Abstract:
Dermal white adipose tissue is a unique layer of adipocytes within the reticular dermis of the skin. Recently, several nonmetabolic activities have been discovered for dWAT and its fibroblast precursors. These functions include antimicrobial defense and roles in hair cycling, wound healing, and thermogenesis. In this review, we discuss recent progress in understanding the role of dermal white adipose tissue in immunity, both as an innate antimicrobial cell type and as an indirect communicator with other cutaneous immunocytes to enhance defense and potentially contribute to inflammatory disease.
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