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Updated: Jan 27, 2026

Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
Quadruple pregnancy after post-IVF/ICSI transfer of blastocysts
M Mercedes Calero Ruiz1, Ana Isabel Mangano Armada2, Javier María Gutiérrez Romero1
1UGC Laboratorios Clínicos Hospital Universitario Puerta del Mar, Cádiz, Spain.
Abstract:
Clinical case of a quadruple pregnancy (monochorionic diamniotic and dichorionic diamniotic) after the transfer of two blastocysts generated by intracytoplasmic sperm injection (ICSI). This is the case of a 29-year-old woman patient with transfer of two blastocysts after long cultivation of 6 embryos generated by ICSI and vitrified on day +3. This revealed quadruple clinical pregnancy (monochorionic diamniotic and dichorionic diamniotic) of 56 days of evolution by transvaginal ultrasound. The couple decided to undergo a selective embryonic reduction of the monochorionic diamniotic pregnancy after receiving information about the risks arising from it. After that embryonic reduction the uncomplicated pregnancy continued until 36 weeks of gestation, achieving reproductive success with the birth of two babies alive and healthy.
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