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Exercise Training Improved Longitudinal Intrinsic Left Ventricle Function in Heart Failure with Preserved Ejection
Anwar Santoso1, Sidhi Laksono Purwowiyoto2, Budhi Setianto Purwowiyoto1
1Department of Cardiology - Vascular Medicine, Faculty of Medicine - Universitas Indonesia, National Cardiovascular Centre - Harapan Kita Hospital, Jakarta, Indonesia.
Summary
Exercise training significantly improved heart function and quality of life in patients with heart failure with preserved ejection fraction (HFPEF). This study demonstrates exercise benefits for HFPEF, enhancing intrinsic left ventricular function and aerobic capacity.
Area of Science:
- Cardiology
- Exercise Physiology
- Cardiac Rehabilitation
Background:
- Exercise benefits are established for heart failure with low ejection fraction (HFrEF).
- Limited data exist on exercise's impact on heart failure with preserved ejection fraction (HFPEF).
- HFPEF is characterized by impaired diastolic function and preserved ejection fraction.
Purpose of the Study:
- To investigate the effects of a structured exercise training program on longitudinal intrinsic left ventricular (LV) function in HFPEF patients.
- To assess improvements in aerobic capacity and quality of life following exercise intervention in HFPEF.
Main Methods:
- A quasi-experimental study involving 30 HFPEF patients.
- A one-month exercise training program with 20 sessions.
- Echocardiography, 6-minute walk tests (6MWTs), and quality-of-life questionnaires were used for evaluation.
Main Results:
- Significant improvements were observed in left ventricular filling pressures and left atrial volume index.
- Longitudinal intrinsic LV function, measured by four-chamber longitudinal strain, augmented significantly (p < 0.001).
- Aerobic capacity (6MWT) and quality of life scores improved significantly (p = 0.001 and p < 0.001, respectively).
Conclusions:
- Exercise training is a viable intervention to enhance longitudinal intrinsic LV function in HFPEF patients.
- Exercise training significantly improves aerobic capacity and quality of life in individuals with HFPEF.
- Further research should explore long-term effects and optimal exercise protocols for HFPEF management.
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