Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Tree of Life - Bacteria, Archaea, Eukaryotes

The Tree of Life - Bacteria, Archaea, Eukaryotes

The “tree of life” describes the evolution of life and the evolutionary relationships between organisms. The root of the tree is the common ancestor to all life on Earth. All other species radiate from this point, much like the branches of a tree. The numerous tips of these branches on the tree of life represent every living, or extant, species. Extinct species, which are species that no longer exist, can be found towards the center of the tree. Currently, these organisms, both...

Survival Tree

Survival Tree

Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
Building a Survival Tree
Constructing a...

The Bronchial Tree

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...

Phylogenetic Trees

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.

Lineage Commitment

Lineage Commitment

Commitment is the process whereby stem cells:

The Tree of Life - Bacteria, Archaea, and Eukaryotes

The Tree of Life - Bacteria, Archaea, and Eukaryotes

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dynamical modeling of individual sensory reactivity and habituation learning.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

ERK inhibits Capicua repressor function via multisite phosphorylation.

Journal of cell science·2026

Same author

Optogenetic control of transition to metamorphosis.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Assessing the relative contributions of mosaic and regulatory developmental modes from single-cell trajectories.

PLoS computational biology·2025

Same author

Disrupted developmental signaling induces novel transcriptional states.

Proceedings of the National Academy of Sciences of the United States of America·2025

Same author

A model for boundary-driven tissue morphogenesis.

Proceedings of the National Academy of Sciences of the United States of America·2025

Search research articles

Related Experiment Video

Updated: Jan 27, 2026

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

Entropic effects in cell lineage tree packings.

Jasmin Imran Alsous^1,2, Paul Villoutreix^2,3, Norbert Stoop⁴

¹Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544.

|March 19, 2019

Summary

This study explores how linked cells pack within confined spaces during early animal development. Findings reveal non-uniform, entropy-driven packing in Drosophila egg chambers, impacting cell organization.

More Related Videos

Co-localization of Cell Lineage Markers and the Tomato Signal

Co-localization of Cell Lineage Markers and the Tomato Signal

Published on: December 28, 2016

A Venturi Effect Can Help Cure Our Trees

A Venturi Effect Can Help Cure Our Trees

Published on: October 1, 2013

Related Experiment Videos

Last Updated: Jan 27, 2026

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

Co-localization of Cell Lineage Markers and the Tomato Signal

Co-localization of Cell Lineage Markers and the Tomato Signal

Published on: December 28, 2016

A Venturi Effect Can Help Cure Our Trees

A Venturi Effect Can Help Cure Our Trees

Published on: October 1, 2013

Area of Science:

Developmental Biology
Biophysics
Mathematical Biology

Background:

Optimal packing of unconnected objects is well-studied, but principles for linked objects remain underexplored.
Topologically complex polymers and cell lineages present unique packing challenges.
Geometrically frustrated tree packing problems arise in early animal development.

Purpose of the Study:

To investigate tree packing problems in geometrically confined environments.
To understand the principles governing positional ordering in linked multicellular structures.
To analyze cell organization during early animal development.

Main Methods:

Utilized 3D imaging and computational image analysis.
Employed mathematical modeling of spherically confined tree packing.
Studied Drosophila egg chambers with 16 interconnected germline cells.

Main Results:

Identified non-uniformly distributed tree packings in Drosophila egg chambers.
Observed packing distributions consistent with energy-based computational predictions.
Demonstrated that non-uniformity is an entropic effect influencing cell organization.

Conclusions:

The study provides a framework for understanding positional ordering in linked multicellular structures.
Results have implications for tissue organization and developmental dynamics.
Highlights the role of geometric frustration and entropy in biological packing.