The Effect of Long-Term X-Ray Exposure on Human Lymphocyte

Area of Science:

• Hematology
• Occupational Health
• Radiation Biology

Background:

• X-ray technicians face prolonged exposure to ionizing radiation.
• Assessing hematological changes, specifically lymphocyte alterations, is crucial for monitoring occupational health.
• Previous studies indicate potential risks, but specific parameter changes require detailed investigation.

Purpose of the Study:

• To investigate the effects of long-term x-ray exposure on human lymphocyte parameters and morphology.
• To compare lymphocyte and reactive lymphocyte counts in X-ray technicians with a control group.
• To evaluate the influence of work experience and daily working hours on these hematological parameters.

Main Methods:

• A case-control study involving 54 X-ray technicians and 54 healthy controls.
• Categorization of technicians based on work experience and daily working hours.
• Complete Blood Cell count (CBC) analysis to assess hematological parameters, focusing on lymphocytes and reactive lymphocytes.

Main Results:

• A highly significant increase (P<0.0001) in reactive lymphocytes was observed in all diagnostic technician groups compared to controls.
• Significant increases in lymphocyte counts were noted in specific technician subgroups.
• Morphological changes in lymphocytes were discernible and correlated with working hours.

Conclusions:

• Chronic x-ray exposure significantly alters lymphocyte and reactive lymphocyte parameters.
• Daily working hours play a discernible role in the observed changes in lymphocyte morphology.
• These findings underscore the importance of radiation safety protocols and health monitoring for X-ray personnel.