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Updated: Jan 27, 2026

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
[Septic arthritis byAggregatibacteraphrophilus: Case report]
Ana María Prestifilippo1, Analía Chajud, Liliana Mobilia
1Hospital San Martín de Paraná.. anamaria110@hotmail.com.
Introduction:
Septic arthritis by Aggregatibacter aphrophilus is an uncommon entity, so it's important to diagnose it early, to avoid serious consequences. In adults, the knee is the most affected site.
Methods:
We present a case of a 17-year-old boy, with pain in the left knee since one month ago. It shows an increase in local temperature, erythema and movement inability. A nuclear magnetic resonance (NMR) was performed and empirical treatment was given with cephalothin and clindamycin. A knee arthrotomy was realized, and intramedullary secretion and bone tissue was sent to study.
Results:
the NMR images were suggestive of an infectious process. In the culture gram-negative coccobacilli were isolated, later identified like as Aggregatibacter aphrophilus. According to this diagnostic, the treatment was changed to ceftriaxone
The Main Conclusions:
the rapidity and certainty in the choice of antimicrobial therapy is the most important step for a well evolution of this infection, therefore is very important to emphasize the importance of a correct identification of these rare microorganisms
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