Related Experiment Video

Updated: Jan 27, 2026

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

848

Primary gastrointestinal aspergillosis: a case report and literature review

Bahadir Ceylan1, Mesut Yilmaz1, Hüseyin Saffet Beköz2

  • 1Medipol University, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Turkey.

Le Infezioni in Medicina
|March 19, 2019
PubMed

Insights

Primary gastrointestinal aspergillosis is a rare but severe infection. This case highlights the importance of considering invasive aspergillosis in neutropenic patients with gastrointestinal symptoms.

Area of Science:

  • Medical Mycology
  • Gastroenterology
  • Hematology

Background:

  • Invasive aspergillosis typically affects the lungs, with primary gastrointestinal involvement being exceptionally rare.
  • Patients undergoing autologous stem cell transplantation are at high risk for opportunistic infections due to profound neutropenia.

Observation:

  • A 65-year-old patient developed febrile neutropenia post-stem cell transplant for gastric non-Hodgkin's lymphoma.
  • The patient presented with abdominal pain and ileus, progressing despite empirical treatment.
  • Intestinal perforation occurred, confirmed aspergillosis on pathological examination.

Findings:

  • The patient experienced a severe, invasive gastrointestinal aspergillosis.
  • Despite medical and surgical interventions, the patient succumbed to complications.
  • Fungal hyphae consistent with Aspergillus were identified in resected intestinal tissue.

Implications:

  • Early recognition of gastrointestinal aspergillosis is crucial in immunocompromised patients.
  • This case underscores the need for high clinical suspicion for invasive fungal infections in neutropenic patients with GI distress.
  • Prompt diagnosis and targeted antifungal therapy may improve outcomes for this rare condition.

More Related Videos

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

11.0K
Gastrointestinal Motility Monitor GIMM08:15

Gastrointestinal Motility Monitor GIMM

Published on: December 1, 2010

31.5K

Related Concept Videos

Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.1K
Anatomy of the Gastrointestinal System01:26

Anatomy of the Gastrointestinal System

The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
2.8K
Histology of the Gastrointestinal (GI) Tract01:20

Histology of the Gastrointestinal (GI) Tract

The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
3.4K
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
1.2K
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K