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Updated: Jan 27, 2026
09:17
High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
15.2K
Comparing phase and electrographic flow mapping for persistent atrial fibrillation
M Swerdlow1, M Tamboli1, M I Alhusseini1
1Cardiovascular Medicine, Stanford University, Stanford, California.
Pacing and Clinical Electrophysiology : PACE
|March 19, 2019
Summary
Electrographic flow mapping (EGF) and phase mapping effectively identify atrial fibrillation (AF) sources. EGF detected more localized sources globally than phase mapping, offering complementary insights for AF ablation strategies.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Imaging
Background:
- Atrial fibrillation (AF) mapping methods are evolving, but their sensitivity in identifying localized AF sources remains unclear.
- Persistent AF ablation success relies on accurate source identification.
Purpose of the Study:
- To compare the sensitivity and effectiveness of electrographic flow mapping (EGF) and phase mapping in identifying localized atrial fibrillation (AF) sources.
- To assess if these mapping methods can detect AF termination sites.
Main Methods:
- A multicenter registry of 53 patients with persistent AF undergoing ablation was analyzed.
- Simultaneous electrograms from a 64-pole basket catheter were used for both EGF and phase mapping.
- The ability of each method to detect localized sources at AF termination sites and global mapping patterns was evaluated.
Main Results:
- Both EGF and phase mapping identified localized sources at AF termination sites in 81% and 83% of patients, respectively.
- EGF identified significantly more localized sources globally compared to phase mapping (5.3 vs 1.8, P < 0.001).
- EGF revealed a higher prevalence of focal activation patterns (49%) compared to rotational patterns (2%).
Conclusions:
- Electrographic flow mapping (EGF) is a novel vectorial-based method that effectively detects AF termination sites.
- EGF results agree with and complement traditional phase mapping methods.
- These findings support the utility of EGF as a valuable tool in AF mapping and ablation guidance.
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