Parent-reported symptoms of ADHD in young people with epilepsy before and two years after epilepsy surgery

Colin Reilly1, Tove Hallböök1, Gerd Viggedal1

  • 1Dept. of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden.

Insights

Pediatric epilepsy surgery significantly reduced parent-reported attention-deficit/hyperactivity disorder (ADHD) symptoms two years post-operation. Seizure freedom and right-sided surgery were linked to symptom improvement in children with ADHD.

Area of Science:

  • Pediatric Neurology
  • Neuropsychology
  • Epileptology

Background:

  • Attention-deficit/hyperactivity disorder (ADHD) is frequently observed in children with epilepsy.
  • Epilepsy surgery is a treatment option for refractory epilepsy, but its impact on comorbid ADHD symptoms requires investigation.

Purpose of the Study:

  • To evaluate changes in parent-reported ADHD symptoms in children before and two years after undergoing epilepsy surgery.
  • To identify factors associated with ADHD symptom improvement following pediatric epilepsy surgery.

Main Methods:

  • A cohort of 107 children completed the Conners 10-item scale for ADHD symptoms at baseline and 2-year follow-up.
  • Paired sample t-tests analyzed score changes; linear regression identified associated factors.

Main Results:

  • Parent-rated ADHD symptoms significantly decreased at follow-up (p < 0.001).
  • Improvements were most notable in core ADHD diagnostic criteria.
  • Higher baseline ADHD scores, seizure-free status, and right-sided surgery were independently associated with symptom improvement.

Conclusions:

  • Parent-reported ADHD symptoms improve 2 years after pediatric epilepsy surgery.
  • Assessment for ADHD at baseline and follow-up is recommended for all children undergoing epilepsy surgery.
  • Seizure control and surgical site may influence ADHD symptom trajectory post-surgery.

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