Related Experiment Video
Updated: Jan 27, 2026

Probing C84-embedded Si Substrate Using Scanning Probe Microscopy and Molecular Dynamics
Published on: September 28, 2016
Extending substrate sensing capabilities of zinc tris(2-pyridylmethyl)amine-based stereodynamic probe
Francesca A Scaramuzzo1, Elena Badetti1, Giulia Licini1
1Dipartimento di Scienze Chimiche, Università degli Studi di Padova, Padova, Italy.
Abstract:
Tripodal metal complexes have been widely used for catalysis and more recently also for molecular recognition applications. Their ability in recognition and signal amplification of chiral substrates is because of the setup of the ligand around the metal in a propeller shape. Within this subject, we have recently reported tris(2-pyridylmethyl)amine- and triphenolamine-based complexes for the determination of the enantiomeric excess of various substrates. Herein, we show the versatility of the zinc tris(2-pyridylmethyl)amine-based stereodynamic probe by performing a detailed study of the imine formation process, by the extension of the sensing capabilities to other chiral compounds. A principal component analysis study of the system together with TD-DFT studies highlights the molecular origin of the observed chiroptical properties.
More Related Videos
Related Concept Videos
2° Amines to N-Nitrosamines: Reaction with NaNO2
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Amines to Amides: Acylation of Amines
Next, the second equivalent of amine serves as a Brønsted base and deprotonates the quaternary...
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by...
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism
Preparation of Amines: Alkylation of Ammonia and Amines
Each alkylation step makes the nitrogen center more nucleophilic, which triggers successive alkylations until a quaternary ammonium salt is formed. Considering...

