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Updated: Jan 27, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Percutaneous Coronary Intervention following Placement of Sutureless Aortic Bioprostheses
Kiran Kaur1, Miryea Cisneros1, Sandeep Nathan1
11 Department of Medicine, Section of Cardiology, Heart and Vascular Center, University of Chicago Medicine, Chicago, IL, USA.
Insights
Minimally invasive aortic valve replacement with sutureless valves followed by transradial percutaneous coronary intervention offers a hybrid approach for patients with severe aortic stenosis and coronary artery disease, minimizing risk.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Co-existing severe aortic stenosis and coronary artery disease presents a complex clinical challenge.
- Established sternal-sparing options exist for isolated aortic valve replacement, but combined non-sternotomy treatment remains undefined.
- Minimally invasive surgical and transcatheter approaches are increasingly utilized for aortic valve disease.
Observation:
- This case series reports on three patients with severe aortic stenosis and obstructive coronary artery disease.
- Patients underwent minimally invasive aortic valve replacement using sutureless valves.
- This was followed by transradial percutaneous coronary intervention for coronary artery disease management.
Findings:
- A hybrid technique combining minimally invasive aortic valve replacement with transradial percutaneous coronary intervention was successfully applied.
- This approach effectively addressed both severe aortic stenosis and significant coronary artery disease.
- The combined treatment strategy demonstrated potential for managing both conditions concurrently with reduced risk.
Implications:
- This hybrid strategy offers a viable non-sternotomy treatment option for patients with combined aortic stenosis and coronary artery disease.
- Further research is warranted to validate the long-term efficacy and safety of this hybrid approach.
- This technique may expand treatment options for complex cardiovascular patients, improving outcomes.
Abstract:
Coronary artery disease is often present with aortic stenosis. Although transcatheter aortic valve replacement and minimally invasive surgery provide alternative sternal-sparing options for isolated aortic valve replacement, non-sternotomy treatment of combined coronary artery disease and aortic stenosis has not been well-defined. We report 3 patients who presented with severe aortic stenosis and obstructive coronary artery disease in whom minimally invasive aortic valve replacement using sutureless valve was performed, followed by transradial percutaneous coronary intervention of obstructive coronary lesion. This case series demonstrates a hybrid technique for the treatment of combined severe aortic stenosis and coronary artery disease, which has potential for adequately treating both conditions with minimal risk.
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