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Published on: June 3, 2022
Decreased opioid prescribing in children using an enhanced recovery protocol
Katherine J Baxter1, Heather L Short1, Martha Wetzel2
1Division of Pediatric Surgery, Department of Surgery, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA.
Insights
Implementing an Enhanced Recovery Protocol (ERP) for pediatric gastrointestinal surgery significantly reduced post-discharge opioid prescriptions. This protocol also lowered length of stay and in-hospital opioid use in young patients.
Area of Science:
- Pediatric Surgery
- Pain Management
- Enhanced Recovery Protocols
Background:
- Previous implementation of an Enhanced Recovery Protocol (ERP) for pediatric elective gastrointestinal operations showed reduced length of stay (LOS) and in-hospital opioid use.
- The study hypothesized that the ERP would also decrease postdischarge opioid prescribing.
Purpose of the Study:
- To evaluate the impact of an Enhanced Recovery Protocol (ERP) on postdischarge opioid prescribing in pediatric patients undergoing elective gastrointestinal surgery.
Main Methods:
- A retrospective cohort study compared demographic, operative, and opioid prescription data.
- Data were analyzed from elective gastrointestinal surgical patients before the ERP (January 2012–December 2014) and after the ERP (January 2015–December 2017).
Main Results:
- Patients receiving an opioid prescription at discharge decreased from 69.8% pre-ERP to 30.9% post-ERP (p < 0.01).
- Intraoperative and postoperative opioid use also significantly decreased in the post-ERP period.
- Length of stay reduced from a median of 4 days to 3 days (p = 0.02).
Conclusions:
- The pediatric gastrointestinal surgery Enhanced Recovery Protocol (ERP) was associated with a significant reduction in postdischarge opioid prescribing.
- The findings support the broader benefits of ERP in pediatric surgical care, extending beyond in-hospital outcomes.
Background:
A previously implemented Enhanced Recovery Protocol (ERP) for children undergoing elective gastrointestinal operations demonstrated decreased length of stay (LOS) and in-hospital opioid use. We hypothesized that the ERP would be associated with decreased postdischarge opioid prescribing.
Methods:
Demographic, operative, and opioid prescription data were retrospectively compared between elective gastrointestinal surgical patients in the pre-ERP (1/2012-12/2014) and the post-ERP periods (1/2015-12/2017).
Results:
Of the 99 patients reviewed, 56 (56.7%) were treated in the post-ERP era. Overall, 48 (48.5%) were male, and the most common operation was partial or total colectomy (n = 39, 39.4%) followed by ileocecectomy (n = 26, 26.3%). Most patients were 15-16 years of age and had inflammatory bowel disease (n = 88, 88.9%). LOS decreased from a median 4 days pre-ERP to 3 days post-ERP (p = 0.02). Patients receiving intraoperative opioids decreased from 100% to 46% (p < 0.01) and postoperative opioids from 95% to 59% (p < 0.01). Patients receiving an opioid prescription at discharge decreased from 69.8% pre-ERP to 30.9% post-ERP (p < 0.01). Among patients prescribed opioids at discharge, the number of doses (median 23 to 17, p = 0.44) and the median morphine equivalents/kg remained stable (median 2.3 to 1.7, p = 0.10).
Conclusions:
A pediatric gastrointestinal surgery ERP resulted in decreased postdischarge prescribing of opioids.
Type Of Study:
Retrospective cohort study.
Level Of Evidence:
Level II.
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