Mitral valve repair based on intraoperative objective measurement

Area of Science:

• Cardiovascular Surgery
• Biomedical Engineering
• Medical Devices

Background:

• Mitral valve repair (MVR) requires precise adjustment of neochordae length.
• Accurate intraoperative assessment of chordae tension is crucial for successful MVR.
• Current methods for neochordae length and tension assessment lack precision and objectivity.

Purpose of the Study:

• To present an innovative system for optimal neochordae length adjustment during transapical MVR.
• To enable real-time measurement and recording of chordae tension during MVR.
• To provide objective intraoperative data to enhance the understanding and outcomes of MVR.

Main Methods:

• Development of a novel system for transapical neochordae implantation.
• Integration of real-time measurement capabilities for chordae tension.
• In vivo data collection from 10 patients undergoing mitral valve repair.

Main Results:

• The system demonstrated optimal length adjustment, increasing accuracy and reproducibility.
• Real-time measurement of chordae tension was successfully achieved, generating novel physiological data.
• Preliminary data provided the first in vivo assessment of chordae tension in human hearts during MVR.

Conclusions:

• The novel system offers precise neochordae length adjustment and objective tension measurement.
• This technology has the potential to shift MVR from qualitative to quantitative analysis.
• The device provides valuable intraoperative data to improve understanding and outcomes of mitral valve repair.