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Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR RS-PCR
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Staphylococcus capitis Osteomyelitis: Case Report.

David Brooks1, Vincent Thomas2, Jessica Snowden3

  • 1University of Nebraska Medical Center, Omaha, NE, USA.

Global Pediatric Health
|March 20, 2019
PubMed
Summary

This case report details a rare invasive Staphylococcus capitis infection causing osteomyelitis in a child with congenital heart disease. It emphasizes considering heteroresistance in staphylococcal infections for unexpected clinical courses.

Keywords:
Coagulase negative staphylococciStaphylococcus capitisosteomyelitis; endocarditis

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Area of Science:

  • Pediatric Infectious Diseases
  • Bacterial Pathogenesis
  • Clinical Case Studies

Background:

  • Coagulase-negative staphylococci (CoNS) are infrequent causes of osteomyelitis, particularly in patients without orthopedic implants.
  • Congenital heart disease can predispose individuals to certain infections, though its direct link to CoNS osteomyelitis is uncommon.
  • Osteomyelitis requires prompt diagnosis and treatment to prevent complications such as bone destruction and systemic spread.

Observation:

  • A pediatric case of invasive infection with Staphylococcus capitis presenting as acute osteomyelitis is described.
  • The patient had a history of repaired congenital heart disease, an unusual comorbidity for this type of infection.
  • The clinical presentation was acute, suggesting a rapidly progressing infectious process.

Findings:

  • Staphylococcus capitis, a CoNS, was identified as the causative agent of osteomyelitis.
  • The absence of an implanted device in the bone makes this a rare presentation of CoNS osteomyelitis.
  • The case suggests a potential link between the underlying cardiac condition and the unusual infection, warranting further investigation.
  • Methicillin heteroresistance in Staphylococcus capitis was considered due to the unexpected clinical course.

Implications:

  • This case underscores the importance of considering less common pathogens like Staphylococcus capitis in pediatric osteomyelitis, especially in complex patients.
  • Clinicians should evaluate for underlying or associated infections when encountering unusual presentations of staphylococcal osteomyelitis.
  • The possibility of methicillin heteroresistance should be investigated in staphylococcal infections that do not respond to standard treatment protocols.
  • This report contributes to the understanding of rare invasive CoNS infections in pediatric populations with cardiac anomalies.