Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

40.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.3K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.1K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.1K
Behavior of Concrete Under Compressive Load01:23

Behavior of Concrete Under Compressive Load

618
Concrete exhibits specific behaviors under different compressive loads. Understanding this is crucial for understanding its structural integrity. When concrete undergoes uniaxial compression, it tends to develop cracks that run parallel to the direction of the force. These parallel cracks stem from localized tensile stresses that occur perpendicular to the compression direction. Additionally, angled cracks may appear due to the formation of shear planes.
As the concrete specimen fractures under...
618
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.1K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.1K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

15.9K
The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
15.9K
Data Collection II01:29

Data Collection II

9.8K
The nursing history captures and records the patient's health status, so that a care plan evolves to meet the patient's individual needs. The nursing health history is a part of the initial assessment. A comprehensive history covers all health dimensions and plays a significant role in the assessment process. A comprehensive history includes the patient's biographical information, reasons for seeking health care, expectations, present and past health history, medications, and...
9.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diet quality and adherence to nutritional recommendations: a multicenter study based on caregiver-child dyads.

Cadernos de saude publica·2026
Same author

Faster run-length compressed suffix arrays.

Oasics : openaccess series in informatics·2026
Same author

Management of Complications After Pancreaticoduodenectomy: A Narrative Review of Pathophysiology and Treatment Strategies.

Cureus·2026
Same author

A simple grammar-based index for finding approximately longest common substrings.

International Symposium on String Processing and Information Retrieval : SPIRE ... : proceedings. SPIRE (Symposium)·2025
Same author

Role of Neoadjuvant Therapy in Remodeling Surgical Approaches for Gastrointestinal Malignancies.

Current gastroenterology reports·2025
Same author

Faster Maximal Exact Matches with Lazy LCP Evaluation.

Proceedings. Data Compression Conference·2024

Related Experiment Video

Updated: Jan 27, 2026

Calibrated Forceps Model of Spinal Cord Compression Injury
09:41

Calibrated Forceps Model of Spinal Cord Compression Injury

Published on: April 24, 2015

19.3K

Compressed filesystem for managing large genome collections.

Gonzalo Navarro1,2, Víctor Sepúlveda1, Mauricio Marín1,3

  • 1CeBiB-Center for Biotechnology and Bioengineering, Santiago, Chile.

Bioinformatics (Oxford, England)
|March 20, 2019
PubMed
Summary
This summary is machine-generated.

A new compressed filesystem uses Relative Lempel-Ziv to efficiently store and access large genome collections. This approach exploits inter-genome similarities for significant data reduction and faster network transfers, benefiting genomic data management.

More Related Videos

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation
10:43

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation

Published on: May 18, 2013

42.7K
Ultra-long Read Sequencing for Whole Genomic DNA Analysis
10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

23.9K

Related Experiment Videos

Last Updated: Jan 27, 2026

Calibrated Forceps Model of Spinal Cord Compression Injury
09:41

Calibrated Forceps Model of Spinal Cord Compression Injury

Published on: April 24, 2015

19.3K
A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation
10:43

A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation

Published on: May 18, 2013

42.7K
Ultra-long Read Sequencing for Whole Genomic DNA Analysis
10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

23.9K

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Data Storage

Background:

  • Genomic data storage is rapidly expanding, exceeding current storage and processing capacities.
  • Individual genomes have limited compressibility, but large repositories of related genomes offer compression opportunities.

Purpose of the Study:

  • To develop a highly compressed filesystem for large-scale genome and read storage.
  • To enable efficient data access and processing without modifying existing applications.

Main Methods:

  • Implementation of a specialized filesystem leveraging Relative Lempel-Ziv algorithm.
  • Exploitation of inter-genome similarities within species for compression.
  • Development of a client/server variant for distributed data access and transfer.

Main Results:

  • Achieved orders-of-magnitude compression for genome repositories.
  • Transparent file compression and decompression without application modification.
  • Significant reduction in network transfer times through compressed data transmission.

Conclusions:

  • The developed compressed filesystem offers a scalable solution for managing large genomic datasets.
  • Relative Lempel-Ziv effectively reduces storage and network overhead for genomic data.
  • Transparent access ensures compatibility with existing bioinformatics tools and workflows.