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Related Experiment Video

Updated: Jan 27, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

MRI for prostate cancer: can computed high b-value DWI replace native acquisitions?

Salma Jendoubi¹, Mathilde Wagner^2,3, Sarah Montagne^1,2

¹Department of Radiology, Tenon Academic Hospital, AP-HP, Sorbonne Universités, Paris, France.

European Radiology

|March 20, 2019

Summary

Computed diffusion-weighted imaging (c-DWI) offers improved prostate MRI quality and lesion conspicuity. This technique reduces scan time while maintaining prostate cancer detection rates, enhancing diagnostic efficiency.

Keywords:

Diagnostic imaging Diffusion-weighted MRI Magnetic resonance imaging Prostatic neoplasms

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Last Updated: Jan 27, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

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Published on: April 9, 2019

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

Area of Science:

Radiology
Medical Imaging
Oncology

Background:

Prostate cancer diagnosis relies heavily on Magnetic Resonance Imaging (MRI).
Diffusion-weighted imaging (DWI) is crucial for detecting prostate cancer.
High b-value DWI can improve lesion conspicuity but increases acquisition time.

Purpose of the Study:

To compare computed high b-value diffusion-weighted images (c-DWI) with acquired high b-value DWI (a-DWI).
To evaluate differences in overall image quality and prostate cancer detection rates.
To assess the impact of c-DWI on MRI acquisition time.

Main Methods:

124 men with suspected prostate cancer underwent 3.0T MRI, including various DWI b-values.
Computed DWI (c-DWI) images were derived from lower b-value images.
c-DWI and acquired DWI (a-DWI) were compared for image quality and tumor conspicuity by four radiologists.

Main Results:

c-DWI showed higher overall image quality ratings than a-DWI.
Prostate cancer detection rates were similar between c-DWI and a-DWI.
c-DWI demonstrated improved lesion conspicuity (p < 0.001) and reduced total acquisition time by 220 seconds per patient.

Conclusions:

Computed DWI significantly reduces MRI acquisition time.
c-DWI maintains comparable prostate cancer detection rates to a-DWI.
c-DWI enhances global image quality, background suppression, and lesion conspicuity in prostate MRI.